Charcot-Marie-Tooth Disease

Also called: Hereditary motor and sensory neuropathy.

What is Charcot-Marie-Tooth Disease?

Charcot-Marie-Tooth disease (CMT) is a group of genetic nerve disorders. It is named after the three doctors who first identified it. In the United States, CMT affects about 1 in 2,500 people. CMT affects your peripheral nerves. Peripheral nerves carry movement and sensation signals between the brain and spinal cord and the rest of the body. Symptoms usually start around the teen years. Foot problems such as high arches or hammertoes can be early symptoms. As CMT progresses, your lower legs may weaken. Later, your hands may also become weak. Doctors diagnose CMT by doing a neurologic exam, nerve tests, genetic tests, or a nerve biopsy. There is no cure. The disease can be so mild you don't realize you have it or severe enough to make you weak. Physical therapy, occupational therapy, braces and other devices and sometimes surgery can help. NIH: National Institute of Neurological Disorders and Stroke

Related topics

Source: MedlinePlus, U.S. National Library of Medicine (NIH) — read the full NIH article.

Educational summary of an authoritative source — not medical advice. Please see your doctor for diagnosis, and seek urgent care for any severe or sudden symptoms.