Is Amiloride safe while breastfeeding?
Here is what NIH LactMed, the U.S. National Library of Medicine's authority on medicines and breastfeeding, reports about Amiloride. This is a summary of that source — not our own verdict.
Effects on the breastfed infant
Relevant published information was not found as of the revision date.
Effects on milk supply
Intense diuresis can suppress lactation;[ 1 , 2 ] however, it is unlikely that amiloride alone is sufficiently potent to cause this effect. A woman with Gitelman syndrome was prescribed amiloride 5 mg daily. She became pregnant and delivered a healthy infant. Amiloride was initially discontinued during breastfeeding, but restarted at 6 weeks postpartum. While on amiloride, the baby s laboratory values showed a serum potassium of 5.8 mmol/L and a serum magnesium of 2.3 mg/dL. Spot urine concentrations of magnesium were 1.4 mg/dL, urine creatinine was 5 mg/dL, and urine potassium was 5 mmol/L. Amiloride was stopped for one week and laboratory tests were repeated. Serum potassium was 4.8 mmol/L, magnesium was 2.2 mg/dL and a urine magnesium concentration was 1.7 mg/dL. Urine creatinine was 8 mg/dL, and urine potassium was 6 mmol/L.[ 3 ]
Levels in milk
Relevant published information was not found as of the revision date.
Alternatives LactMed lists
Source: NIH LactMed (National Library of Medicine).
Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.