Is Aspartame safe while breastfeeding?
Here is what NIH LactMed, the U.S. National Library of Medicine's authority on medicines and breastfeeding, reports about Aspartame. This is a summary of that source — not our own verdict.
Effects on the breastfed infant
A cross-sectional survey assessed the dietary history of US mothers nursing infants between 11 and 15 weeks of age. The survey was used to estimate the amount of diet soda and fruit drinks consumed by the women. There were no statistically significant differences in infants weight or z-scores based on low calorie sweetener exposure. However, infants exposed to low calorie sweetener in milk once or less per week had a statistically significantly higher risk of vomiting than those who were not exposed. Greater exposure was not associated with vomiting. It was not possible to assess the effects of specific sweeteners.[ 4 ] A retrospective dietary recall study compared the use of diet soda and aspartame during pregnancy and/or lactation to the risk of autism in the children. Among boys, autism was associated with three times the likelihood of exposure to aspartame. No statistically significant associations were found in girls.[ 5 ] The contribution of exposure during breastfeeding was not separated from the risk of exposure during pregnancy, and intact aspartame is usually not found in milk, so breastmilk exposure cannot be claimed to cause autism based on these data. The authors propose that the methanol metabolite might have an impact on infants.
Effects on milk supply
Relevant published information was not found as of the revision date.
Levels in milk
Aspartame is rapidly metabolized in the body to 2 amino acids that occur naturally in breastmilk, aspartic acid and phenylalanine and methanol. Maternal Levels. Six lactating women an average of 98 days postpartum (range 42 to 159 days) were given aspartame or lactose orally in a dose of 50 mg/kg (equivalent to 17 aspartame-sweetened sodas or 100 packets of Equal in a 68 kg [150 lb.] adult[ 1 ]) on 2 separate occasions 2 weeks apart in a randomized crossover trial. Breastmilk samples were collected over the next 24 hours. Breastmilk phenylalanine levels increased to a maximum of about 6 mg/L between 1 and 8 hours after the dose of aspartame and returned to baseline by about 12 hours after the dose. Lactose had no effect on breastmilk phenylalanine levels. Aspartame was not detected ( 1.4 mg/L) in breastmilk at any time. The authors calculated that if the milk phenylalanine concentration were elevated for 24 hours to the maximum found in this study, a fully breastfed infant would receive an additional 0.5 mg/kg daily above the normal intake of 79 mg/kg of phenylalanine that occurs naturally in breastmilk.[ 2 ] Twenty lactating women completed background questionnaires about breastfeeding and the intake of nonnutritive sweeteners in the prior 24 hours. Each then donated a milk sample that was analyzed for the presence of nonnutritive sweeteners. Sweetener intake was primarily from diet sodas and sweetener packets. Of the 14 women who reported intake of a nonnutritive sweetener, none had quantifiable levels of aspartame in their breastmilk.[ 3 ] Infant Levels. Relevant published information was not found as of the revision date.
Source: NIH LactMed (National Library of Medicine).
Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.