Is Atogepant safe while breastfeeding?
Here is what NIH LactMed, the U.S. National Library of Medicine's authority on medicines and breastfeeding, reports about Atogepant. This is a summary of that source — not our own verdict.
Effects on the breastfed infant
Relevant published information was not found as of the revision date.
Effects on milk supply
Relevant published information was not found as of the revision date.
Levels in milk
Maternal Levels . Twelve healthy lactating adult women 1 to 6 months postpartum were given a single 60 mg oral dose of atogepant in a multicenter study. Milk samples were collected prior to the dose and over the following intervals: 0 to 2, 2 to 4, 4 to 8, 8 to 12, 12 to 16, and 16 to 24 hours after the dose. The average peak milk level occurred at an average of 2 hours (range 1 to 3 hours) and averaged 75 mcg/L. A total of 9 mcg was excreted into milk over the collection period and the calculated relative infant dose averaged 0.19%.[ 1 ] Infant Levels . Relevant published information was not found as of the revision date.
Alternatives LactMed lists
“No published information” means the studies do not exist yet — not that Atogepant is known to be harmful, and not that it is known to be safe. Your prescriber or pharmacist can weigh your baby's age and whether a better-studied alternative would do the same job. Worth asking before stopping a medicine you need.
Source: NIH LactMed (National Library of Medicine).
Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.