Is Bacampicillin safe while breastfeeding?

Here is what NIH LactMed, the U.S. National Library of Medicine's authority on medicines and breastfeeding, reports about Bacampicillin. This is a summary of that source — not our own verdict.

Effects on the breastfed infant

Bacampicillin is rapidly converted to ampicillin. Some adverse reactions from ampicillin have been reported. An uncontrolled observation of the breastfed infants of mothers taking ampicillin noted a seeming increase in cases of diarrhea and candidiasis that was attributed to ampicillin in breastmilk.[ 2 ] In a prospective follow-up study, 5 nursing mothers reported taking ampicillin (dosage unspecified). One mother reported diarrhea in her infant. No rashes or candidiasis were reported among the exposed infants.[ 3 ] A small, controlled, prospective study had mothers monitor their infants for signs of adverse effects (furring of the tongue, feeding difficulties, changes in stool frequency and consistency, diaper rash, and skin rash). Weight change and the development of jaundice were also recorded. No statistical differences in these parameters were found between the infants of the control mothers and those of mothers taking ampicillin.[ 4 ] Naproxen possibly caused prolonged bleeding time, thrombocytopenia and acute anemia in one 7-day-old infant in a mother also taking bacampicillin.[ 5 ] The role of bacampicillin in this reaction is unknown.

Effects on milk supply

Relevant published information was not found as of the revision date.

Levels in milk

Maternal Levels. Only traces of drug could be detected in breastmilk after a 500 mg oral dose of bacampicillin in 2 women.[ 1 ] Infant Levels. Relevant published information was not found as of the revision date.

Source: NIH LactMed (National Library of Medicine).

Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.