Is Belatacept safe while breastfeeding?
Here is what NIH LactMed, the U.S. National Library of Medicine's authority on medicines and breastfeeding, reports about Belatacept. This is a summary of that source — not our own verdict.
Effects on the breastfed infant
A mother with a liver transplant was maintained on belatacept 10 mg/kg monthly, slow-release tacrolimus (Envarsus and Veloxis) 2 mg daily, azathioprine 25 mg daily, and prednisone 2.5 mg daily. She breastfed her infant for a year (extent not stated). The infant s growth and cognitive milestones were normal.[ 2 ] In a case series from the Transplant Pregnancy Registry International of women who received belatacept during pregnancy and postpartum, 5 women with kidney transplants breastfeed their 7 children while continuing belatacept infusions with no reports of problems breastfeeding or issues in the children. The duration and extent of breastfeeding was not reported in 4 instances, but in the other 3, the durations were 1 month, 2 months, and 4 weeks exclusive breastfeeding, followed by partial breastfeeding.[ 3 ] A review of the Transplant Pregnancy Registry International database from 1999 to 2024 found that 6 mothers with transplants had breastfed their infants for at least 4 weeks while taking belatacept.[ 4 ] These 6 probably included the 5 women reported above.
Effects on milk supply
Relevant published information was not found as of the revision date.
Levels in milk
Maternal Levels . Relevant published information was not found as of the revision date. Infant Levels . Relevant published information was not found as of the revision date.
Alternatives LactMed lists
Source: NIH LactMed (National Library of Medicine).
Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.