Is Delamanid safe while breastfeeding?
Here is what NIH LactMed, the U.S. National Library of Medicine's authority on medicines and breastfeeding, reports about Delamanid. This is a summary of that source — not our own verdict.
Effects on the breastfed infant
Relevant published information was not found as of the revision date.
Effects on milk supply
Relevant published information was not found as of the revision date.
Levels in milk
Maternal Levels. The breastmilk of two patients receiving delamanid in unspecified doses had peak delamanid milk levels 4 hours after a dose. One had a peak delamanid milk level of about 200 mcg/L and a level of the active metabolite DM-6705 that was undetectable ( 10 mcg/L) at all time points. The second woman had a peak delamanid level of about 700 mcg/L and a peak milk level of the active metabolite DM-6705 of about 40 mcg/L at 4 hours after the dose. Because the serum level of the first patient was also low, it was thought that her adherence to the regimen was poor.[ 1 ] Infant Levels. Relevant published information was not found as of the revision date.
“No published information” means the studies do not exist yet — not that Delamanid is known to be harmful, and not that it is known to be safe. Your prescriber or pharmacist can weigh your baby's age and whether a better-studied alternative would do the same job. Worth asking before stopping a medicine you need.
Source: NIH LactMed (National Library of Medicine).
Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.