Is Desmopressin safe while breastfeeding?
Here is what NIH LactMed, the U.S. National Library of Medicine's authority on medicines and breastfeeding, reports about Desmopressin. This is a summary of that source — not our own verdict.
Effects on the breastfed infant
Relevant published information was not found as of the revision date.
Effects on milk supply
Several cases have been reported of mothers with diabetes insipidus using desmopressin and breastfeeding their infants.[ 2 - 4 ] In one case, the mother discontinued nursing after 2 weeks because of a low milk supply, but this was not clearly drug related.[ 3 ] Lactation sometimes improves diabetes insipidus and reduces desmopressin requirements.[ 2 , 3 ]
Levels in milk
Maternal Levels. In a patient who was using intranasal desmopressin 10 mcg twice daily for diabetes insipidus, serum and milk levels of arginine vasopressin were measured after a dose.[ 1 ] Milk levels gradually increased from the background level of 1 ng/L to about 1.5 ng/L over the 4-hour observation period. Infant Levels. Relevant published information was not found as of the revision date.
Source: NIH LactMed (National Library of Medicine).
Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.