Is Diazoxide safe while breastfeeding?
Here is what NIH LactMed, the U.S. National Library of Medicine's authority on medicines and breastfeeding, reports about Diazoxide. This is a summary of that source — not our own verdict.
Effects on the breastfed infant
One infant was partially breastfed (10 to 50% initially, then 80% at 1 month of age) by a mother taking diazoxide orally in dosages of 150 to 175 mg daily for hypoglycemia. At 30 days of age, the infant was developing normally and had experienced no episodes of hypo- or hyperglycemia.[ 1 ]
Effects on milk supply
Relevant published information was not found as of the revision date.
Levels in milk
Maternal Levels. A woman with nesidioblastosis hypoglycemia had been on diazoxide for 30 years since the age of 4 months. Diazoxide was stopped during her pregnancies, but reinstated at week 25 of her second pregnancy in a dose of 50 mg three times daily and later the dosage schedule was 50 mg, 50 mg and 75 mg after her third meal of the day. Milk samples were taken 6 times between day 3 and day 8 postpartum. The highest concentrations in milk were 2.4 mg/L at 3 hours after a 50 mg dose and 3.1 mg/L at 3.4 hours after a 75 mg dose. The lowest measured level was 0.7 mg/L at 9 hours after a 75 mg dose.[ 1 ] Infant Levels. Relevant published information was not found as of the revision date.
Source: NIH LactMed (National Library of Medicine).
Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.