Is Etizolam safe while breastfeeding?
Here is what NIH LactMed, the U.S. National Library of Medicine's authority on medicines and breastfeeding, reports about Etizolam. This is a summary of that source — not our own verdict.
Effects on the breastfed infant
A woman took etizolam 1 mg and trazodone 50 mg once daily for 3 months postpartum. Her infant was over 50% breastfed and demonstrated no adverse reactions at the 1- and 3-month checkups.[ 2 ]
Effects on milk supply
Relevant published information was not found as of the revision date.
Levels in milk
Maternal Levels. One woman who was taking oral etizolam 1 mg daily donated milk samples between 3 and 6 days postpartum at 1 hour after a dose at the estimated peak serum concentration and just before a dose. She had a 1-hour milk level of 0.77 mcg/L and a trough milk level of 0.9 mcg/L.[ 1 ] A woman took etizolam 1 mg and trazodone 50 mg once daily for 3 months postpartum. A milk sample on day 7 postpartum at 11.5 hours after the dose contained 1 mcg/L of etizolam. Four milk samples taken on day 35 postpartum from 15.5 to 25 hours after the dose contained etizolam in concentrations from 0.41 mcg/L to 0.2 mcg/L, respectively. On day 36 postpartum, milk samples at 6.5 and 13.5 hours after the dose contained 0.67 and 0.39 mcg/L of etizolam. The authors estimated that the maximum dose the infant would receive in milk was 0.15 mcg/kg daily which corresponds to 0.95% of the maternal weight-adjusted dosage.[ 2 ] Infant Levels. Relevant published information was not found as of the revision date.
Alternatives LactMed lists
Source: NIH LactMed (National Library of Medicine).
Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.