Is Norepinephrine safe while breastfeeding?
Here is what NIH LactMed, the U.S. National Library of Medicine's authority on medicines and breastfeeding, reports about Norepinephrine. This is a summary of that source — not our own verdict.
Effects on the breastfed infant
Relevant published information was not found as of the revision date.
Effects on milk supply
Norepinephrine inhibits the synthesis of beta-casein via stimulation of adrenergic beta-2 receptors.[ 1 ] Animal data indicate that norepinephrine can decrease serum prolactin and reduce milk production,[ 3 ] as well as inhibit the release of oxytocin, which inhibits milk ejection.[ 4 ]
Levels in milk
Maternal Levels. Eight nursing mothers collected breastmilk for analysis of norepinephrine. Milk norepinephrine levels ranged from 2.1 to 19.5 mcg/L (12.7 to 115.5 nanomolar). The norepinephrine in milk appears to be synthesized locally by mammary epithelial cells and actively secreted into milk.[ 1 , 2 ] Infant Levels. Relevant published information was not found as of the revision date.
Source: NIH LactMed (National Library of Medicine).
Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.