Is Norovirus Vaccine safe while breastfeeding?
Here is what NIH LactMed, the U.S. National Library of Medicine's authority on medicines and breastfeeding, reports about Norovirus Vaccine. This is a summary of that source — not our own verdict.
Effects on the breastfed infant
Relevant published information was not found as of the revision date.
Effects on milk supply
Relevant published information was not found as of the revision date.
Levels in milk
Maternal Levels. An oral bivalent norovirus vaccine (viral capsid protein of GI.1 and GII.4) was studied in south Africa. Sixteen women were given a placebo, 30 were in the medium-dose group (5 x 10 10 IU/genotype), and 30 were in the high-dose group (1x 10 11 IU/genotype). Vaccinated medium and high-dose groups highest levels of GI.1-specific breastmilk IgA were observed on day 29 post vaccination, with a mean fold rise of 5.57 and 4.04, respectively, compared to 1.40 in the placebo group. Breastmilk GI.1-specific IgA remained above baseline through day 180 with a mean fold rise of 2.28 and 2.08 in the medium and high-dose groups compared to 1.35 in the placebo group. Infant stool IgA concentrations were also increased.[ 1 ] Infant Levels. Relevant published information was not found as of the revision date.
“No published information” means the studies do not exist yet — not that Norovirus Vaccine is known to be harmful, and not that it is known to be safe. Your prescriber or pharmacist can weigh your baby's age and whether a better-studied alternative would do the same job. Worth asking before stopping a medicine you need.
Source: NIH LactMed (National Library of Medicine).
Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.