Is Pretomanid safe while breastfeeding?
Here is what NIH LactMed, the U.S. National Library of Medicine's authority on medicines and breastfeeding, reports about Pretomanid. This is a summary of that source — not our own verdict.
Effects on the breastfed infant
Relevant published information was not found as of the revision date.
Effects on milk supply
Relevant published information was not found as of the revision date.
Levels in milk
Maternal Levels. Using a computed milk-to-plasma ratio of 0.89, one group of authors estimated that a fully breastfed infant would receive a pretomanid dosage of 1.02 mcg/kg daily with a standard maternal dose of 200 mg daily.[ 1 ] However, the authors used a nonstandard milk volume in their calculation. Using the standard 150 mL/kg daily, the estimated infant dosage would be 0.83 mcg/kg daily. Infant Levels. Relevant published information was not found as of the revision date.
“No published information” means the studies do not exist yet — not that Pretomanid is known to be harmful, and not that it is known to be safe. Your prescriber or pharmacist can weigh your baby's age and whether a better-studied alternative would do the same job. Worth asking before stopping a medicine you need.
Source: NIH LactMed (National Library of Medicine).
Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.