Is Semaglutide safe while breastfeeding?
Here is what NIH LactMed, the U.S. National Library of Medicine's authority on medicines and breastfeeding, reports about Semaglutide. This is a summary of that source — not our own verdict.
Effects on the breastfed infant
Eight nursing mothers were using subcutaneous semaglutide in doses ranging from 0.25 to 1 mg weekly. Their infants ranged in age from 4 to 23 months of age and were mixed fed. They were fed breastmilk for 3 to 9 weeks while their mothers were taking semaglutide. All of the infants were reported to have normal growth and development by their mothers.[ 1 ]
Effects on milk supply
Relevant published information was not found as of the revision date.
Levels in milk
Maternal Levels. Eight nursing mothers, who were using subcutaneous semaglutide in doses ranging from 0.25 to 1 mg weekly, donated milk samples at 0,12 and 24 hours after a dose. None of the samples contained any measurable semaglutide ( 1.7 mcg/L). The authors calculated that if milk had contained semaglutide at the detection limit, the relative infant dose would have averaged only 1.12%.[ 1 ] This does not take into consideration that the drug is poorly absorbed orally, with a maximum bioavailability of 1% in adults. Infant Levels. Relevant published information was not found as of the revision date.
Alternatives LactMed lists
Source: NIH LactMed (National Library of Medicine).
Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.