Is Streptomycin safe while breastfeeding?
Here is what NIH LactMed, the U.S. National Library of Medicine's authority on medicines and breastfeeding, reports about Streptomycin. This is a summary of that source — not our own verdict.
Effects on the breastfed infant
Relevant published information was not found as of the revision date.
Effects on milk supply
One observational study found no inhibition of lactation by streptomycin.[ 1 ]
Levels in milk
Maternal Levels. Forty-six mothers receiving intramuscular streptomycin 250,000 MU had milk streptomycin levels measured hourly after a dose. The peak concentration in milk averaged 0.64 MU and occurred 9 hours after the dose. Mothers with unilateral mastitis had higher levels in the breast with mastitis than in the unaffected breast.[ 1 ] Although it is not clear what the above dose was in milligrams in this older Russian paper, if the same proportion is used, a 1 g intramuscular dose would result in a peak streptomycin milk level of 2.6 mg/L. Infant Levels. Relevant published information was not found as of the revision date.
Source: NIH LactMed (National Library of Medicine).
Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.