Is Velpatasvir safe while breastfeeding?
Here is what NIH LactMed, the U.S. National Library of Medicine's authority on medicines and breastfeeding, reports about Velpatasvir. This is a summary of that source — not our own verdict.
Effects on the breastfed infant
Relevant published information was not found as of the revision date.
Effects on milk supply
Relevant published information was not found as of the revision date.
Levels in milk
Maternal Levels . Four mothers with hepatitis C infections began taking velpatasvir 100 mg in combination with sofosbuvir 400 mg orally once daily shortly after delivery. Paired samples of maternal serum and breastmilk were collected within the first 24 hours after commencing the drug regimen and at up to 6 days after initiation. Samples were collected from 1 to 25.6 hours after a dose. The median velpatasvir milk concentration was 26.8 mcg/L (range 6.6 to 59.7 mcg/L) with a median infant daily dosage of 4 mcg/kg and a relative infant dose of 0.14%.[ 5 ] Because of the random collection and the reporting method, the true values may vary somewhat from these numbers. Infant Levels . Relevant published information was not found as of the revision date.
Alternatives LactMed lists
“No published information” means the studies do not exist yet — not that Velpatasvir is known to be harmful, and not that it is known to be safe. Your prescriber or pharmacist can weigh your baby's age and whether a better-studied alternative would do the same job. Worth asking before stopping a medicine you need.
Source: NIH LactMed (National Library of Medicine).
Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.