Can I take alogliptin while pregnant or breastfeeding?
A plain-words look at what the NHS, the US drug label and LactMed say about alogliptin.
In short
Pregnancy: Let your doctor know if you're pregnant, or if you become pregnant while on alogliptin.
Breastfeeding: Let your doctor know if you're breastfeeding.
Your doctor, midwife or pharmacist can help you decide.
What this means for you
Pregnancy
- Alogliptin is not used in pregnancy.
- Your doctor may suggest that you stop it or change to another medicine.
Breastfeeding
- Alogliptin is not usually used during breastfeeding.
- Your doctor will suggest that you stop it or change to another medicine.
Talk to your doctor or pharmacist
This page is educational, not advice for your own situation. Talk to your doctor, midwife or pharmacist before you start, stop or change any medicine in pregnancy or while breastfeeding.
The details: what each source says
Alogliptin in pregnancy
The NHS says
Let your doctor know if you're pregnant, or if you become pregnant while on alogliptin.
Alogliptin is not used in pregnancy. Your doctor may suggest that you stop it or change to another medicine.
In our words, from the NHS page Alogliptin (nhs.uk). Contains public sector information licensed under the Open Government Licence v3.0 (OGL v3.0). The NHS does not endorse this site.
The US drug label says
8.1 Pregnancy Risk Summary Limited data with alogliptin in pregnant women are not sufficient to determine a drug-associated risk for major birth defects or miscarriage.
Prescribing label, section “8.1 Pregnancy” (opening excerpt): Alogliptin (oral), Padagis Israel Pharmaceuticals Ltd. Read the full section on DailyMed. Quoted verbatim; US labels are written for US prescribers and patients.
More on alogliptin in pregnancy: Bumps (Best Use of Medicines in Pregnancy) leaflet (external site).
Alogliptin while breastfeeding
The NHS says
Let your doctor know if you're breastfeeding.
Alogliptin is not usually used during breastfeeding. Your doctor will suggest that you stop it or change to another medicine.
In our words, from the NHS page Alogliptin (nhs.uk). Contains public sector information licensed under the Open Government Licence v3.0 (OGL v3.0). The NHS does not endorse this site.
LactMed says
No information is available on the clinical use of alogliptin during breastfeeding. An alternate drug may be preferred, especially while nursing a newborn or preterm infant. Monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with alogliptin.[1]
“Summary of Use during Lactation”, LactMed record “Alogliptin” (LM1062), quoted verbatim. Everything LactMed reports about Alogliptin while breastfeeding.
The US prescribing label says
8.2 Lactation Risk Summary There is no information regarding the presence of alogliptin in human milk, the effects on the breastfed infant, or the effects on milk production. Alogliptin is present in rat milk: however, due to species specific differences in lactation physiology, animal lactation data may not reliably predict levels in human milk . The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for alogliptin tablets and any potential adverse effects on the breastfed infant from alogliptin tablets or from the underlying maternal condition.
Prescribing label, section “8.2 Lactation”: Alogliptin (oral), Padagis Israel Pharmaceuticals Ltd. Label on DailyMed. Quoted verbatim; US labels are written for US prescribers and patients.
Sources
- NHS, Alogliptin (nhs.uk), page last reviewed 23 July 2026. Paraphrased. Contains public sector information licensed under the Open Government Licence v3.0.
- US drug label: Alogliptin (oral), Padagis Israel Pharmaceuticals Ltd, human prescription drug, label effective 11 April 2025, set ID b25f155a-1259-47c2-aa3b-7c1356e4c7f6. DailyMed (National Library of Medicine). Public domain; quoted verbatim.
- Drugs and Lactation Database (LactMed), National Institute of Child Health and Human Development (NICHD), via NCBI Bookshelf, record “Alogliptin” (LM1062), bulk release of 22 September 2026. LactMed on NCBI Bookshelf. Public domain; quoted verbatim. LactMed is a registered trademark of the U.S. Department of Health and Human Services.
- Bumps (Best Use of Medicines in Pregnancy), UK Teratology Information Service: Bumps (Best Use of Medicines in Pregnancy) leaflet. Linked, not reproduced.
Sources checked 26 September 2026. How we source and check every page.
Educational summary of named sources, not medical advice.