Can I take indapamide while pregnant or breastfeeding?
A plain-words look at what the NHS, the US drug label and LactMed say about indapamide.
In short
Pregnancy: Let your doctor know if you're pregnant, or become pregnant while you're on indapamide.
Breastfeeding: Let your doctor know if you're breastfeeding.
Your doctor, midwife or pharmacist can help you decide.
What this means for you
Pregnancy
- Indapamide is not usually recommended in pregnancy.
Breastfeeding
- Indapamide is not usually used while breastfeeding, because small amounts may get into breast milk.
Talk to your doctor or pharmacist
This page is educational, not advice for your own situation. Talk to your doctor, midwife or pharmacist before you start, stop or change any medicine in pregnancy or while breastfeeding.
The details: what each source says
Indapamide in pregnancy
The NHS says
Let your doctor know if you're pregnant, or become pregnant while you're on indapamide.
Indapamide is not usually recommended in pregnancy.
In our words, from the NHS page Indapamide (nhs.uk). Contains public sector information licensed under the Open Government Licence v3.0 (OGL v3.0). The NHS does not endorse this site.
The US drug label says
Pregnancy: Teratogenic Effects: Reproduction studies have been performed in rats, mice and rabbits at doses up to 6,250 times the therapeutic human dose and have revealed no evidence of impaired fertility or harm to the fetus due to indapamide. Postnatal development in rats and mice was unaffected by pre-treatment of parent animals during gestation. There are, however, no adequate and well-controlled studies in pregnant women. Moreover, diuretics are known to cross the placental barrier and appear in cord blood. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. There may be hazards associated with this use such as fetal or neonatal jaundice, thrombocytopenia, and possibly other adverse reactions that have occurred in the adult.
Prescribing label, section “Pregnancy”: Indapamide (oral), Preferred Pharmaceuticals Inc. Label on DailyMed. Quoted verbatim; US labels are written for US prescribers and patients.
Indapamide while breastfeeding
The NHS says
Let your doctor know if you're breastfeeding.
Indapamide is not usually used while breastfeeding, because small amounts may get into breast milk.
In our words, from the NHS page Indapamide (nhs.uk). Contains public sector information licensed under the Open Government Licence v3.0 (OGL v3.0). The NHS does not endorse this site.
LactMed says
No information is available on the amount of indapamide in breastmilk. Intense diuresis with large doses may decrease breastmilk production. Other diuretics in low doses are preferred over indapamide.
“Summary of Use during Lactation”, LactMed record “Indapamide” (LM144), quoted verbatim. Everything LactMed reports about Indapamide while breastfeeding.
The US prescribing label says
Nursing Mothers: It is not known whether this drug is excreted in human milk. Because most drugs are excreted in human milk, if use of this drug is deemed essential, the patient should stop nursing.
Prescribing label, section “Nursing Mothers”: Indapamide (oral), Preferred Pharmaceuticals Inc. Label on DailyMed. Quoted verbatim; US labels are written for US prescribers and patients.
Sources
- NHS, Indapamide (nhs.uk), page last reviewed 3 July 2026. Paraphrased. Contains public sector information licensed under the Open Government Licence v3.0.
- US drug label: Indapamide (oral), Preferred Pharmaceuticals Inc., human prescription drug, label effective 13 May 2026, set ID 59cd3331-7afe-432a-8b50-39533fd5f392. DailyMed (National Library of Medicine). Public domain; quoted verbatim.
- Drugs and Lactation Database (LactMed), National Institute of Child Health and Human Development (NICHD), via NCBI Bookshelf, record “Indapamide” (LM144), bulk release of 22 September 2026. LactMed on NCBI Bookshelf. Public domain; quoted verbatim. LactMed is a registered trademark of the U.S. Department of Health and Human Services.
Sources checked 26 September 2026. How we source and check every page.
Educational summary of named sources, not medical advice.