Is Ceftizoxime safe while breastfeeding?
Here is what NIH LactMed, the U.S. National Library of Medicine's authority on medicines and breastfeeding, reports about Ceftizoxime. This is a summary of that source — not our own verdict.
Effects on the breastfed infant
Relevant published information was not found as of the revision date.
Effects on milk supply
Relevant published information was not found as of the revision date.
Levels in milk
Maternal Levels. After a single 1 gram intravenous dose of ceftizoxime in 2 women, milk levels ranged from 0.31 to 0.43 mg/L from 2 to 8 hours after the dose. The peak milk level occurred at 2 hours after the dose in one and 6 hours after the dose in the other.[ 1 ] Five women were given 1 gram of ceftizoxime intravenously. Average peak milk levels of 0.39 mg/L occurred 3 hours after the dose, although individuals had peak levels ranging from 0.31 mg/L at 3 hours after the dose to 0.83 mg/L at 6 hours after the dose. Four of the women had undetectable milk levels by 6 hours after the dose.[ 2 ] In six women given 1 gram of ceftizoxime intravenously, average milk levels were 0.25 mg/L 1 hour after the dose.[ 3 ] After a single 1 gram intravenous dose in 2 women, ceftizoxime milk levels were measurable only 4 hours after the dose and averaged 0.1 mg/L.[ 4 ] Infant Levels. Relevant published information was not found as of the revision date.
“No published information” means the studies do not exist yet — not that Ceftizoxime is known to be harmful, and not that it is known to be safe. Your prescriber or pharmacist can weigh your baby's age and whether a better-studied alternative would do the same job. Worth asking before stopping a medicine you need.
Source: NIH LactMed (National Library of Medicine).
Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.