Is Ceftriaxone safe while breastfeeding?
Here is what NIH LactMed, the U.S. National Library of Medicine's authority on medicines and breastfeeding, reports about Ceftriaxone. This is a summary of that source — not our own verdict.
Effects on the breastfed infant
A mother who was exclusively nursing her 52-day-old infant developed a soft-tissue infection. She was treated with intravenous teicoplanin 400 mg every 12 hours for 3 doses, then 400 mg daily for 5 days total, intravenous ceftriaxone 1 gram daily, topical mupirocin cream twice daily. A careful follow-up indicated that her infant had no adverse effects.[ 2 ]
Effects on milk supply
Relevant published information was not found as of the revision date.
Levels in milk
Maternal Levels. Following administration of a 1 gram dose of ceftriaxone intramuscularly or intravenously on day 3 postpartum to 20 women, peak milk levels averaged about 0.7 and 0.5 mg/L, respectively. Peaks occurred about 4 hours after the dose and fell very slowly over 24 hours with half-lives of 13 to 17 hours. The amounts in milk represent an infant dosage of about 0.5% of the maternal weight-adjusted dosage.[ 1 ] Infant Levels. Relevant published information was not found as of the revision date.
Source: NIH LactMed (National Library of Medicine).
Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.